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Gilead

Senior Director, Toxicologic Pathologist

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

Job Description

Gilead’s Pathobiology group provides intellectual and experimental input across all of R&D to advance discovery, translational research and nonclinical safety activities including target identification/validation, biomarker development and implementation, and drug development. The high-functioning team includes pathologists and scientists, and partners closely with other groups within Gilead plus an extensive network of external CROs and experts.

We are seeking a forward-thinking, enthusiastic Toxicologic Pathologist with pharmaceutical/biotech experience to lead our toxicologic pathology function. Candidate should have a consistent track record in partnering with scientific colleagues to identify and seek critical questions related to pathobiology issues in drug discovery and development. Candidate will work closely with our project toxicologists to design studies, interpret data and make decisions related to nonclinical safety projects and risk assessments. The role will involve some peer review of non-GLP and GLP studies, plus extensive interactions with Gilead Toxicologists and project teams, and with CROs and external pathologists. The pathologist will be a pivotal expert resource and provide guidance for Toxicologic Pathology input across the R&D portfolio. An aptitude to operate in a matrix-style environment is essential.

The Pathologist will be strongly encouraged to become involved with the other major functions of the Pathobiology group, including translational/biomarker science and research pathology. Experience in these other areas is highly desirable, consistent with our strategy to utilize pathobiology knowledge and input across full spectrum of R&D. The Pathobiology group includes a highly innovative and experienced scientific team with excellent skills and advanced technological capabilities (IHC, C/FISH, multiplexing, TMAs, image analysis etc.). Pathologists work closely with this team, assisting with assay planning, development and interpretation. The position will report into the Head of Pathobiology. Gilead is a fast-paced, scientifically rigorous organization, and the role will suit a pathologist who is able to thrive in this type of environment.

Minimum Qualifications:

  • You have a DVM or MD, with a PhD in a relevant biological discipline
  • Recognized board certification in anatomic pathology
  • At least 5+ years of toxicologic pathology experience in a pharmaceutical R&D environment, including screening, IND-enabling and development studies in rodent and non-rodent species
  • Demonstrated issue-resolution experience
  • High level of understanding of the drug discovery, development and regulatory process, including experience working directly on drug development project teams and Regulatory Authority interactions and submissions
  • Demonstrated innovative, flexible and critical thinking applied to R&D pathobiology
  • Demonstrated interpersonal and communication skills
  • Able to project opinions and knowledge with confidence, authority, respect and diplomacy when interacting with all levels of Gilead colleagues and external partners
  • Excellent leadership and delegation skills demonstrated by successfully mentoring and motivating people in a matrix and/or line organization
  • Working knowledge of modern pathology laboratory technologies, including assay development, application and interpretation

Preferred Qualifications:

  • Experience of translational/clinical biomarker and/or research pathology in a pharmaceutical R&D environment.
  • Experience of molecular pathology assay development (IHC, ISH, RNASeq, qPCR, LCM), data integration and analysis, image analysis and interpretation.

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For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

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